{"id":2882,"date":"2026-01-29T17:23:17","date_gmt":"2026-01-29T14:23:17","guid":{"rendered":"https:\/\/wiki.dev.voka.io\/glossary\/bolha\/"},"modified":"2026-01-29T17:23:34","modified_gmt":"2026-01-29T14:23:34","slug":"bolha","status":"publish","type":"glossary_item","link":"https:\/\/wiki.dev.voka.io\/pt\/glossario\/bolha\/","title":{"rendered":"Bula"},"content":{"rendered":"\n

Uma bula (do latim bulla<\/em>) \u00e9 uma cavidade prim\u00e1ria grande (mais de 0,5-1 cm de di\u00e2metro) cheia de l\u00edquido. \u00c9 essencialmente uma “grande ves\u00edcula”. As bolhas podem estar localizadas intraepidermicamente (na epiderme) ou subepidermicamente (sob a epiderme). <\/p>\n\n

O “revestimento” da bexiga pode estar tenso ou fl\u00e1cido.<\/p>\n\n

Etiologia e fisiopatologia<\/strong><\/h2>\n\n

As causas da forma\u00e7\u00e3o de bolhas est\u00e3o frequentemente associadas a processos patol\u00f3gicos graves: <\/p>\n\n

    \n
  • Factores mec\u00e2nicos:<\/strong> Fric\u00e7\u00e3o (calosidades). <\/li>\n\n\n\n
  • Factores t\u00e9rmicos:<\/strong> Queimaduras de segundo grau. <\/li>\n\n\n\n
  • Doen\u00e7as auto-imunes:<\/strong> Ves\u00edculas vesiculares (acant\u00f3lise – perda de liga\u00e7\u00e3o entre as c\u00e9lulas epid\u00e9rmicas), penfigoide bolhoso. <\/li>\n\n\n\n
  • Reac\u00e7\u00f5es t\u00f3xico-al\u00e9rgicas:<\/strong> S\u00edndrome de Lyell.<\/li>\n<\/ul>\n\n

    Significado cl\u00ednico<\/strong><\/h2>\n\n

    A presen\u00e7a de bolhas indica frequentemente a gravidade da les\u00e3o cut\u00e2nea. Quando a bolha se rompe, forma-se uma grande superf\u00edcie erosiva, que \u00e9 uma porta de entrada para a infe\u00e7\u00e3o e resulta numa perda significativa de fluidos e prote\u00ednas corporais. <\/p>\n","protected":false},"excerpt":{"rendered":"

    Uma bula (do latim bulla<\/em>) \u00e9 uma cavidade prim\u00e1ria grande (mais de 0,5-1 cm de di\u00e2metro) cheia de l\u00edquido. \u00c9 essencialmente uma “grande ves\u00edcula”. As bolhas podem estar localizadas intraepidermicamente (na epiderme) ou subepidermicamente (sob a epiderme). <\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-2882","glossary_item","type-glossary_item","status-publish","hentry"],"acf":[],"yoast_head":"\nBula: defini\u00e7\u00e3o m\u00e9dica e vis\u00e3o geral | Voka Wiki<\/title>\n<meta name=\"description\" content=\"Uma bula (do latim bulla) \u00e9 uma cavidade prim\u00e1ria grande (mais de 0,5-1 cm de di\u00e2metro) cheia de l\u00edquido. \u00c9 essencialmente uma "grande ves\u00edcula". 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