{"id":664,"date":"2025-05-07T12:48:33","date_gmt":"2025-05-07T09:48:33","guid":{"rendered":"https:\/\/wiki.dev.voka.io\/diseases\/uncategorized\/paragangliome\/"},"modified":"2026-04-24T10:28:45","modified_gmt":"2026-04-24T07:28:45","slug":"paragangliome","status":"publish","type":"diseases_post","link":"https:\/\/wiki.dev.voka.io\/fr\/maladies\/systeme-vasculaire\/paragangliome\/","title":{"rendered":"Ch\u00e9modectome (paragangliome) : \u00e9tiologie, pathog\u00e9nie, classification, diagnostic, m\u00e9thodes de traitement"},"content":{"rendered":"<p><?xml encoding=\"UTF-8\" ?><\/p>\n<p>\u041f\u0430\u0440\u0430\u0433\u0430\u043d\u0433\u043b\u0438\u043e\u043c\u0430 \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u043e\u0433\u043e \u0442\u0435\u043b\u044c\u0446\u0430 (\u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430) \u2014 \u0440\u0435\u0434\u043a\u0430\u044f, \u043f\u0440\u0435\u0438\u043c\u0443\u0449\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e \u0434\u043e\u0431\u0440\u043e\u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f \u043e\u043f\u0443\u0445\u043e\u043b\u044c, \u0432\u043e\u0437\u043d\u0438\u043a\u0430\u044e\u0449\u0430\u044f \u0438\u0437 \u0445\u0435\u043c\u043e\u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u043d\u044b\u0445 \u043a\u043b\u0435\u0442\u043e\u043a \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u043e\u0433\u043e \u0442\u0435\u043b\u0430, \u0440\u0430\u0441\u043f\u043e\u043b\u043e\u0436\u0435\u043d\u043d\u043e\u0433\u043e \u0432 \u043c\u0435\u0441\u0442\u0435 \u0431\u0438\u0444\u0443\u0440\u043a\u0430\u0446\u0438\u0438 \u043e\u0431\u0449\u0435\u0439 \u0441\u043e\u043d\u043d\u043e\u0439 \u0430\u0440\u0442\u0435\u0440\u0438\u0438.<\/p>\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/articles\/en\/vascular-system\/paraganglioma\/chemodectoma-paraganglioma.webp\" alt=\"Ch\u00e9modectome (paragangliome)\"><figcaption class=\"wp-element-caption\">\u0425\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430 (\u043f\u0430\u0440\u0430\u0433\u0430\u043d\u0433\u043b\u0438\u043e\u043c\u0430) \u2013 <a href=\"https:\/\/catalog.voka.io\/ru\/models\/6e2f9dc5-6e91-46c4-b881-b038f53acd05\/6ec65686-8390-42c1-b3f3-c7a1f7148948\/aa66bddd-72b2-4945-91b8-90210e91fc55\/9db48cfc-4d8c-4de0-8e9c-e20a7d131626\" target=\"_blank\" rel=\"noreferrer noopener nofollow\">3D-\u043c\u043e\u0434\u0435\u043b\u044c<\/a><\/figcaption><\/figure>\n<h2 class=\"wp-block-heading\" id=\"epidemiologie\">\u00c9pid\u00e9miologie  <\/h2>\n<ul class=\"wp-block-list\">\n<li>Environ 1 \u00e0 2 cas pour 100 000 habitants. <\/li>\n<li>Les femmes sont plus souvent touch\u00e9es que les hommes. <\/li>\n<li>L\u2019\u00e2ge moyen du diagnostic est d\u2019environ 45 ans.<\/li>\n<li>\u0412\u044b\u0441\u043e\u043a\u0430\u044f \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u043e\u0442\u043c\u0435\u0447\u0430\u0435\u0442\u0441\u044f \u0432 \u0441\u0442\u0440\u0430\u043d\u0430\u0445 \u041b\u0430\u0442\u0438\u043d\u0441\u043a\u043e\u0439 \u0410\u043c\u0435\u0440\u0438\u043a\u0438, \u043e\u0441\u043e\u0431\u0435\u043d\u043d\u043e \u0432 \u041c\u0435\u043a\u0441\u0438\u043a\u0435, \u0433\u0434\u0435 \u0436\u0435\u043d\u0449\u0438\u043d\u044b \u0441\u043e\u0441\u0442\u0430\u0432\u043b\u044f\u044e\u0442 \u0434\u043e 90 % \u0441\u043b\u0443\u0447\u0430\u0435\u0432.<\/li>\n<li>Les habitants des r\u00e9gions de haute altitude ont un risque accru de d\u00e9velopper des chimiodectomes en raison de l\u2019hypoxie chronique.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\" id=\"etiologie\">\u00c9tiologie<\/h2>\n<p><strong>\u0413\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043c\u0443\u0442\u0430\u0446\u0438\u0438<\/strong> \u2014 \u0432\u0435\u0434\u0443\u0449\u0443\u044e \u0440\u043e\u043b\u044c \u0438\u0433\u0440\u0430\u044e\u0442 \u043c\u0443\u0442\u0430\u0446\u0438\u0438 \u0432 \u0433\u0435\u043d\u0430\u0445, \u043a\u043e\u0434\u0438\u0440\u0443\u044e\u0449\u0438\u0445 \u0441\u0443\u0431\u044a\u0435\u0434\u0438\u043d\u0438\u0446\u044b \u0441\u0443\u043a\u0446\u0438\u043d\u0430\u0442\u0434\u0435\u0433\u0438\u0434\u0440\u043e\u0433\u0435\u043d\u0430\u0437\u043d\u043e\u0433\u043e \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u0430 (SDH), \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u0443\u0447\u0430\u0441\u0442\u0432\u0443\u0435\u0442 \u0432 \u0434\u044b\u0445\u0430\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0446\u0435\u043f\u0438 \u043c\u0438\u0442\u043e\u0445\u043e\u043d\u0434\u0440\u0438\u0439 \u0438 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u043c \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c\u0435. \u041e\u0441\u043d\u043e\u0432\u043d\u044b\u0435 \u0433\u0435\u043d\u044b:<\/p>\n<ul class=\"wp-block-list\">\n<li><strong><em>SDHD<\/em><\/strong> \u2014 \u043d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u0447\u0430\u0441\u0442\u043e \u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d \u0441 \u043c\u043d\u043e\u0436\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u043c\u0438 \u043f\u0430\u0440\u0430\u0433\u0430\u043d\u0433\u043b\u0438\u043e\u043c\u0430\u043c\u0438 \u0433\u043e\u043b\u043e\u0432\u044b \u0438 \u0448\u0435\u0438; \u043f\u0435\u0440\u0435\u0434\u0430\u0435\u0442\u0441\u044f \u043f\u043e \u043e\u0442\u0446\u043e\u0432\u0441\u043a\u043e\u0439 \u043b\u0438\u043d\u0438\u0438;<\/li>\n<li><strong><em>SDHB<\/em><\/strong> \u2014 \u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d \u0441 \u0431\u043e\u043b\u0435\u0435 \u0430\u0433\u0440\u0435\u0441\u0441\u0438\u0432\u043d\u044b\u043c\u0438 \u0444\u043e\u0440\u043c\u0430\u043c\u0438 \u0438 \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u044b\u043c \u0440\u0438\u0441\u043a\u043e\u043c \u0437\u043b\u043e\u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0433\u043e \u0442\u0435\u0447\u0435\u043d\u0438\u044f;<\/li>\n<li><strong><em>SDHC<\/em><\/strong><strong>, <\/strong><strong><em>SDHA<\/em><\/strong><strong>, <\/strong><strong><em>SDHAF2<\/em><\/strong> \u2014 \u0440\u0435\u0436\u0435 \u0432\u043e\u0432\u043b\u0435\u0447\u0435\u043d\u044b, \u043d\u043e \u0442\u0430\u043a\u0436\u0435 \u043c\u043e\u0433\u0443\u0442 \u0441\u043f\u043e\u0441\u043e\u0431\u0441\u0442\u0432\u043e\u0432\u0430\u0442\u044c \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044e \u043e\u043f\u0443\u0445\u043e\u043b\u0438.<\/li>\n<\/ul>\n<p><strong>\u0421\u0438\u043d\u0434\u0440\u043e\u043c\u044b, <\/strong><strong>\u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0435 \u0441 \u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430\u043c\u0438<\/strong>:\u00a0<\/p>\n<ul class=\"wp-block-list\">\n<li>\u0441\u0438\u043d\u0434\u0440\u043e\u043c \u0444\u043e\u043d \u0413\u0438\u043f\u043f\u0435\u043b\u044f \u2014 \u041b\u0438\u043d\u0434\u0430\u0443 (VHL);\u00a0<\/li>\n<li>\u043c\u043d\u043e\u0436\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f \u044d\u043d\u0434\u043e\u043a\u0440\u0438\u043d\u043d\u0430\u044f \u043d\u0435\u043e\u043f\u043b\u0430\u0437\u0438\u044f 2 \u0442\u0438\u043f\u0430 (MEN2);\u00a0<\/li>\n<li>\u043d\u0435\u0439\u0440\u043e\u0444\u0438\u0431\u0440\u043e\u043c\u0430\u0442\u043e\u0437 1 \u0442\u0438\u043f\u0430 (NF1)\u200b.<\/li>\n<\/ul>\n<p><strong>\u0425\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0433\u0438\u043f\u043e\u043a\u0441\u0438\u044f<\/strong> \u2014 \u043f\u0440\u043e\u0436\u0438\u0432\u0430\u043d\u0438\u0435 \u043d\u0430 \u0432\u044b\u0441\u043e\u0442\u0435 \u0431\u043e\u043b\u0435\u0435 2000 \u043c \u043d\u0430\u0434 \u0443\u0440\u043e\u0432\u043d\u0435\u043c \u043c\u043e\u0440\u044f, \u0430 \u0442\u0430\u043a\u0436\u0435 \u0442\u0430\u043a\u0438\u0435 \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f, \u043a\u0430\u043a \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u043e\u0431\u0441\u0442\u0440\u0443\u043a\u0442\u0438\u0432\u043d\u0430\u044f \u0431\u043e\u043b\u0435\u0437\u043d\u044c \u043b\u0435\u0433\u043a\u0438\u0445 \u0438 \u0432\u0440\u043e\u0436\u0434\u0435\u043d\u043d\u044b\u0435 \u043f\u043e\u0440\u043e\u043a\u0438 \u0441\u0435\u0440\u0434\u0446\u0430, \u043c\u043e\u0433\u0443\u0442 \u0441\u0442\u0438\u043c\u0443\u043b\u0438\u0440\u043e\u0432\u0430\u0442\u044c \u0433\u0438\u043f\u0435\u0440\u043f\u043b\u0430\u0437\u0438\u044e \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u043e\u0433\u043e \u0442\u0435\u043b\u0430. \u200b<\/p>\n<p><strong>\u0421\u0435\u043c\u0435\u0439\u043d\u044b\u0439 \u0430\u043d\u0430\u043c\u043d\u0435\u0437 \u2014 \u043e\u043a\u043e\u043b\u043e 10\u00a0%<\/strong> \u0441\u043b\u0443\u0447\u0430\u0435\u0432 \u044f\u0432\u043b\u044f\u044e\u0442\u0441\u044f \u0441\u0435\u043c\u0435\u0439\u043d\u044b\u043c\u0438.<\/p>\n<div class=\"videos-carousel-block\">\n<div class=\"swiper video-carousel-swiper video-carousel-swiper-block_69ef30110df2e\">\n<div class=\"swiper-wrapper\">\n<div class=\"swiper-slide\"><video controls class=\"carousel-video\"><source data-src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/articles\/Vascular%20Pathology\/%20Chemodectoma\/chemodectoma-type-1.webm\" type=\"video\/webm\"><\/source><\/video><span class=\"small-text-article text-main-text-color\">3D-\u0430\u043d\u0438\u043c\u0430\u0446\u0438\u044f \u2013 \u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430 I \u0442\u0438\u043f<\/span><\/div>\n<div class=\"swiper-slide\"><video controls class=\"carousel-video\"><source data-src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/articles\/Vascular%20Pathology\/%20Chemodectoma\/chemodectoma-type-3.webm\" type=\"video\/webm\"><\/source><\/video><span class=\"small-text-article text-main-text-color\">3D-\u0430\u043d\u0438\u043c\u0430\u0446\u0438\u044f \u2013 \u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430 III \u0442\u0438\u043f<\/span><\/div>\n<\/div>\n<\/div>\n<div class=\"swiper-article-video-carousel__controls\">\n<div class=\"swiper-article-video-carousel__pagination-container swiper-article-video-carousel__pagination-container-block_69ef30110df2e\"><\/div>\n<div class=\"swiper-article-video-carousel__arrows\"><button class=\"swiper__arrow swiper__arrow--prev video-carousel-swiper-button-prev swiper__arrow swiper__arrow--prev video-carousel-swiper-button-prev-block_69ef30110df2e\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"40\" height=\"40\" viewbox=\"0 0 40 40\" fill=\"none\"><path d=\"M20 3.75C16.7861 3.75 13.6443 4.70305 10.972 6.48862C8.29969 8.27419 6.21689 10.8121 4.98696 13.7814C3.75704 16.7507 3.43524 20.018 4.06225 23.1702C4.68926 26.3224 6.23692 29.2179 8.50952 31.4905C10.7821 33.7631 13.6776 35.3107 16.8298 35.9378C19.982 36.5648 23.2493 36.243 26.2186 35.013C29.1879 33.7831 31.7258 31.7003 33.5114 29.028C35.297 26.3557 36.25 23.2139 36.25 20C36.2455 15.6916 34.5319 11.561 31.4855 8.51454C28.439 5.46806 24.3084 3.75455 20 3.75ZM23.3844 25.3656C23.5005 25.4818 23.5926 25.6196 23.6555 25.7714C23.7184 25.9231 23.7507 26.0858 23.7507 26.25C23.7507 26.4142 23.7184 26.5769 23.6555 26.7286C23.5926 26.8804 23.5005 27.0182 23.3844 27.1344C23.2682 27.2505 23.1304 27.3426 22.9786 27.4055C22.8269 27.4683 22.6643 27.5007 22.5 27.5007C22.3358 27.5007 22.1731 27.4683 22.0214 27.4055C21.8696 27.3426 21.7318 27.2505 21.6156 27.1344L15.3656 20.8844C15.2494 20.7683 15.1572 20.6304 15.0943 20.4787C15.0314 20.3269 14.999 20.1643 14.999 20C14.999 19.8357 15.0314 19.6731 15.0943 19.5213C15.1572 19.3696 15.2494 19.2317 15.3656 19.1156L21.6156 12.8656C21.7318 12.7495 21.8696 12.6574 22.0214 12.5945C22.1731 12.5317 22.3358 12.4993 22.5 12.4993C22.6643 12.4993 22.8269 12.5317 22.9786 12.5945C23.1304 12.6574 23.2682 12.7495 23.3844 12.8656C23.5005 12.9818 23.5926 13.1196 23.6555 13.2714C23.7184 13.4231 23.7507 13.5858 23.7507 13.75C23.7507 13.9142 23.7184 14.0769 23.6555 14.2286C23.5926 14.3804 23.5005 14.5182 23.3844 14.6344L18.0172 20L23.3844 25.3656Z\" fill=\"#B5C0CD\"><\/path><\/svg><\/button><button class=\"swiper__arrow swiper__arrow--next video-carousel-swiper-button-next swiper__arrow swiper__arrow--next video-carousel-swiper-button-next-block_69ef30110df2e\" tabindex=\"0\" aria-label=\"Next slide\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"40\" height=\"40\" viewbox=\"0 0 40 40\" fill=\"none\"><path d=\"M20 3.75C16.7861 3.75 13.6443 4.70305 10.972 6.48862C8.29969 8.27419 6.21689 10.8121 4.98696 13.7814C3.75704 16.7507 3.43524 20.018 4.06225 23.1702C4.68926 26.3224 6.23692 29.2179 8.50952 31.4905C10.7821 33.7631 13.6776 35.3107 16.8298 35.9378C19.982 36.5648 23.2493 36.243 26.2186 35.013C29.1879 33.7831 31.7258 31.7003 33.5114 29.028C35.297 26.3557 36.25 23.2139 36.25 20C36.2455 15.6916 34.5319 11.561 31.4855 8.51454C28.439 5.46806 24.3084 3.75455 20 3.75ZM23.3844 25.3656C23.5005 25.4818 23.5926 25.6196 23.6555 25.7714C23.7184 25.9231 23.7507 26.0858 23.7507 26.25C23.7507 26.4142 23.7184 26.5769 23.6555 26.7286C23.5926 26.8804 23.5005 27.0182 23.3844 27.1344C23.2682 27.2505 23.1304 27.3426 22.9786 27.4055C22.8269 27.4683 22.6643 27.5007 22.5 27.5007C22.3358 27.5007 22.1731 27.4683 22.0214 27.4055C21.8696 27.3426 21.7318 27.2505 21.6156 27.1344L15.3656 20.8844C15.2494 20.7683 15.1572 20.6304 15.0943 20.4787C15.0314 20.3269 14.999 20.1643 14.999 20C14.999 19.8357 15.0314 19.6731 15.0943 19.5213C15.1572 19.3696 15.2494 19.2317 15.3656 19.1156L21.6156 12.8656C21.7318 12.7495 21.8696 12.6574 22.0214 12.5945C22.1731 12.5317 22.3358 12.4993 22.5 12.4993C22.6643 12.4993 22.8269 12.5317 22.9786 12.5945C23.1304 12.6574 23.2682 12.7495 23.3844 12.8656C23.5005 12.9818 23.5926 13.1196 23.6555 13.2714C23.7184 13.4231 23.7507 13.5858 23.7507 13.75C23.7507 13.9142 23.7184 14.0769 23.6555 14.2286C23.5926 14.3804 23.5005 14.5182 23.3844 14.6344L18.0172 20L23.3844 25.3656Z\" fill=\"#B5C0CD\"><\/path><\/svg><\/button><\/div>\n<\/div>\n<\/div>\n<p><script defer>\n    document.addEventListener('DOMContentLoaded', function() {\n        const videosCarouselSwiper = new Swiper('.video-carousel-swiper-block_69ef30110df2e', {\n            slidesPerView: 1,\n            spaceBetween: 20,\n            loop: true,\n            pagination: {\n                el: '.swiper-article-video-carousel__pagination-container-block_69ef30110df2e',\n                clickable: true,\n            },\n            navigation: {\n                nextEl: '.video-carousel-swiper-button-next-block_69ef30110df2e',\n                prevEl: '.video-carousel-swiper-button-prev-block_69ef30110df2e',\n            },\n            on: {\n                slideChangeTransitionStart: function () {\n                    const videos = this.el.querySelectorAll('video');\n                    videos.forEach(video => {\n                        if (!video.paused) {\n                            video.pause();\n                            video.currentTime = 0;\n                        }\n                    });\n                },\n            }\n        })\n    })\n<\/script><\/p>\n<h2 class=\"wp-block-heading\" id=\"pathogenie\">Pathog\u00e9nie<\/h2>\n<ol class=\"wp-block-list\">\n<li><strong>\u041d\u0430\u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0435 \u043c\u0443\u0442\u0430\u0446\u0438\u0438 (<em>SDHx<\/em>)<\/strong><\/li>\n<\/ol>\n<p>\u041c\u0443\u0442\u0430\u0446\u0438\u0438 <em>SDH<\/em> (\u043a\u043b\u044e\u0447\u0435\u0432\u043e\u0433\u043e \u0444\u0435\u0440\u043c\u0435\u043d\u0442\u0430 \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u0430 II \u043c\u0438\u0442\u043e\u0445\u043e\u043d\u0434\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0439 \u0434\u044b\u0445\u0430\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0446\u0435\u043f\u0438 \u0438 \u0446\u0438\u043a\u043b\u0430 \u041a\u0440\u0435\u0431\u0441\u0430) \u2192 \u043d\u0430\u043a\u043e\u043f\u043b\u0435\u043d\u0438\u0435 \u0441\u0443\u043a\u0446\u0438\u043d\u0430\u0442\u0430 (\u0434\u0435\u0439\u0441\u0442\u0432\u0443\u0435\u0442 \u043a\u0430\u043a <em>oncometabolite<\/em>) \u2192 \u0438\u043d\u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f \u043f\u0440\u043e\u043b\u0438\u043b\u0433\u0438\u0434\u0440\u043e\u043a\u0441\u0438\u043b\u0430\u0437 (PHDs) \u2014 \u0444\u0435\u0440\u043c\u0435\u043d\u0442\u043e\u0432, \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0438\u0440\u0443\u044e\u0449\u0438\u0445 \u0434\u0435\u0433\u0440\u0430\u0434\u0430\u0446\u0438\u044e HIF-1\u03b1 (\u0433\u0438\u043f\u043e\u043a\u0441\u0438\u044f-\u0438\u043d\u0434\u0443\u0446\u0438\u0440\u0443\u0435\u043c\u043e\u0433\u043e \u0444\u0430\u043a\u0442\u043e\u0440\u0430) \u2192 \u043d\u0430\u043a\u043e\u043f\u043b\u0435\u043d\u0438\u0435 HIF-1\u03b1 \u2192 \u043f\u0441\u0435\u0432\u0434\u043e\u0433\u0438\u043f\u043e\u043a\u0441\u0438\u044f \u2192 \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f VEGF (\u0430\u043d\u0433\u0438\u043e\u0433\u0435\u043d\u0435\u0437) \/ GLUT1 (\u0433\u043b\u0438\u043a\u043e\u043b\u0438\u0437) \/ PDGF (\u043a\u043b\u0435\u0442\u043e\u0447\u043d\u0430\u044f \u043f\u0440\u043e\u043b\u0438\u0444\u0435\u0440\u0430\u0446\u0438\u044f) \u2192 \u043d\u0435\u043e\u043f\u043b\u0430\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0442\u0440\u0430\u043d\u0441\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f \u0445\u0435\u043c\u043e\u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u043d\u044b\u0445 \u043a\u043b\u0435\u0442\u043e\u043a \u0438 \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u0435 \u043e\u043f\u0443\u0445\u043e\u043b\u0438.<\/p>\n<ol start=\"2\" class=\"wp-block-list\">\n<li><strong>Hypoxie chronique<\/strong><\/li>\n<\/ol>\n<p>\u0413\u0438\u043f\u043e\u043a\u0441\u0438\u044f (\u0432\u044b\u0441\u043e\u0442\u0430, \u0425\u041e\u0411\u041b) \u2192 \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 pO\u2082 \u2192 \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u044b\u0445 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u043e\u0432 \u2192 \u0433\u0438\u043f\u0435\u0440\u043f\u043b\u0430\u0437\u0438\u044f \u043a\u043b\u0435\u0442\u043e\u043a \u2192 \u043d\u0430\u043a\u043e\u043f\u043b\u0435\u043d\u0438\u0435 HIF-1\u03b1 \u2192 \u0430\u043d\u0433\u0438\u043e\u0433\u0435\u043d\u0435\u0437 \u0438 \u043d\u0435\u043e\u043f\u043b\u0430\u0437\u0438\u044f.\u00a0<\/p>\n<p>\u0412 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0435 \u043e\u043f\u0443\u0445\u043e\u043b\u044c \u043f\u043e\u0441\u0442\u0435\u043f\u0435\u043d\u043d\u043e \u0443\u0432\u0435\u043b\u0438\u0447\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u0432 \u0440\u0430\u0437\u043c\u0435\u0440\u0430\u0445. \u041f\u043e \u043c\u0435\u0440\u0435 \u0440\u043e\u0441\u0442\u0430 \u043e\u043d\u0430 \u043c\u043e\u0436\u0435\u0442 \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u043e\u0432\u0430\u0442\u044c \u043b\u043e\u043a\u0430\u043b\u044c\u043d\u043e \u0438\u043d\u0432\u0430\u0437\u0438\u0432\u043d\u044b\u0439 \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440, \u0432\u043f\u043b\u043e\u0442\u044c \u0434\u043e \u043e\u043a\u0440\u0443\u0436\u0435\u043d\u0438\u044f \u0438\u043b\u0438 \u0441\u0434\u0430\u0432\u043b\u0435\u043d\u0438\u044f \u0431\u043b\u0438\u0437\u043b\u0435\u0436\u0430\u0449\u0438\u0445 \u0430\u043d\u0430\u0442\u043e\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440, \u0442\u0430\u043a\u0438\u0445 \u043a\u0430\u043a \u0432\u043d\u0443\u0442\u0440\u0435\u043d\u043d\u044f\u044f \u0438 \u043d\u0430\u0440\u0443\u0436\u043d\u0430\u044f \u0441\u043e\u043d\u043d\u044b\u0435 \u0430\u0440\u0442\u0435\u0440\u0438\u0438, \u0431\u043b\u0443\u0436\u0434\u0430\u044e\u0449\u0438\u0439, \u043f\u043e\u0434\u044a\u044f\u0437\u044b\u0447\u043d\u044b\u0439 \u0438 \u044f\u0437\u044b\u043a\u043e\u0433\u043b\u043e\u0442\u043e\u0447\u043d\u044b\u0439 \u043d\u0435\u0440\u0432\u044b. \u042d\u0442\u043e \u043c\u043e\u0436\u0435\u0442 \u0432\u044b\u0437\u044b\u0432\u0430\u0442\u044c \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0443\u044e\u0449\u0443\u044e \u043d\u0435\u0432\u0440\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0443\u044e \u0438 \u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u0443\u044e \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u0430\u0442\u0438\u043a\u0443.<\/p>\n<h2 class=\"wp-block-heading\" id=\"classification-des-paragangliomes\">Classification des paragangliomes<\/h2>\n<p>\u0423\u0438\u043b\u044c\u044f\u043c \u0428\u0430\u043c\u0431\u043b\u0438\u043d \u043f\u0440\u0435\u0434\u043b\u043e\u0436\u0438\u043b \u0434\u0435\u043b\u0438\u0442\u044c \u043f\u0430\u0440\u0430\u0433\u0430\u043d\u0433\u043b\u0438\u043e\u043c\u044b \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u043e\u0433\u043e \u0442\u0435\u043b\u044c\u0446\u0430 \u043d\u0430 \u0442\u0440\u0438 \u0442\u0438\u043f\u0430 (Shamblin-\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u044f):<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u0442\u0438\u043f I<\/strong>: \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u043d\u044b\u0435 \u043e\u043f\u0443\u0445\u043e\u043b\u0438 \u0434\u043e 3,5 \u0441\u043c, \u0440\u044b\u0445\u043b\u043e \u0441\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0435 \u0441\u043e \u0441\u0442\u0435\u043d\u043a\u0430\u043c\u0438 \u0430\u0440\u0442\u0435\u0440\u0438\u0439;<\/li>\n<li><strong>\u0442\u0438\u043f II<\/strong>: 3,5\u20135 \u0441\u043c, \u0447\u0430\u0441\u0442\u0438\u0447\u043d\u043e \u043e\u0445\u0432\u0430\u0442\u044b\u0432\u0430\u044e\u0442 \u0441\u043e\u043d\u043d\u044b\u0435 \u0430\u0440\u0442\u0435\u0440\u0438\u0438, \u0438\u043c\u0435\u044e\u0442 \u0431\u043e\u043b\u0435\u0435 \u043f\u043b\u043e\u0442\u043d\u043e\u0435 \u0441\u0440\u0430\u0449\u0435\u043d\u0438\u0435 \u0441\u043e \u0441\u0442\u0435\u043d\u043a\u0430\u043c\u0438 \u0430\u0440\u0442\u0435\u0440\u0438\u0439;<\/li>\n<li><strong>\u0442\u0438\u043f III<\/strong>: \u0431\u043e\u043b\u0435\u0435 5 \u0441\u043c, \u043e\u0445\u0432\u0430\u0442\u044b\u0432\u0430\u044e\u0442 \u0441\u043e\u043d\u043d\u044b\u0435 \u0430\u0440\u0442\u0435\u0440\u0438\u0438 \u0438\/\u0438\u043b\u0438 \u0431\u043b\u0438\u0437\u043b\u0435\u0436\u0430\u0449\u0438\u0435 \u0441\u043e\u0441\u0443\u0434\u044b, \u043d\u0435\u0440\u0432\u044b \u0438\u043c\u0435\u044e \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u043e \u043f\u043b\u043e\u0442\u043d\u043e\u0435 \u0441\u0440\u0430\u0449\u0435\u043d\u0438\u0435 \u0441 \u0434\u0430\u043d\u043d\u044b\u043c\u0438 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u0430\u043c\u0438.<\/li>\n<\/ul>\n<p>\u041a\u0440\u043e\u043c\u0435 \u0442\u043e\u0433\u043e, \u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0443 \u043c\u043e\u0436\u043d\u043e \u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u0442\u044c <strong>\u043f\u043e \u044d\u0442\u0438\u043e\u043b\u043e\u0433\u0438\u0438<\/strong>: \u0441\u043f\u043e\u0440\u0430\u0434\u0438\u0447\u0435\u0441\u043a\u0430\u044f (\u0434\u043e 85\u00a0%), \u0441\u0435\u043c\u0435\u0439\u043d\u0430\u044f (10\u201315\u00a0%), \u0433\u0438\u043f\u0435\u0440\u043f\u043b\u0430\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f (1\u20135\u00a0%).<\/p>\n<div class=\"carousel-block\">\n<div class=\"swiper carousel-swiper carousel-swiper-block_69ef30110f163\">\n<div class=\"swiper-wrapper\">\n<div class=\"swiper-slide image-carousel-slide\"><img decoding=\"async\" class=\"carousel-image\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/articles\/en\/vascular-system\/paraganglioma\/chemodectoma-type-1.webp\" alt=\"\u0425\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430 I \u0442\u0438\u043f\"><span class=\"small-text-article text-main-text-color\">\u0425\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430 I \u0442\u0438\u043f<\/span><\/div>\n<div class=\"swiper-slide image-carousel-slide\"><img decoding=\"async\" class=\"carousel-image\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/articles\/en\/vascular-system\/paraganglioma\/chemodectoma-type-3.webp\" alt=\"\u0425\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430 III \u0442\u0438\u043f\"><span class=\"small-text-article text-main-text-color\">\u0425\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430 III \u0442\u0438\u043f<\/span><\/div>\n<\/div>\n<\/div>\n<div class=\"swiper-article-carousel__controls\">\n<div class=\"swiper-article-carousel__pagination-container swiper-article-carousel__pagination-container-block_69ef30110f163\"><\/div>\n<div class=\"swiper-article-carousel__arrows\"><button class=\"swiper__arrow swiper__arrow--prev carousel-swiper-button-prev swiper__arrow swiper__arrow--prev carousel-swiper-button-prev-block_69ef30110f163\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"40\" height=\"40\" viewbox=\"0 0 40 40\" fill=\"none\"><path d=\"M20 3.75C16.7861 3.75 13.6443 4.70305 10.972 6.48862C8.29969 8.27419 6.21689 10.8121 4.98696 13.7814C3.75704 16.7507 3.43524 20.018 4.06225 23.1702C4.68926 26.3224 6.23692 29.2179 8.50952 31.4905C10.7821 33.7631 13.6776 35.3107 16.8298 35.9378C19.982 36.5648 23.2493 36.243 26.2186 35.013C29.1879 33.7831 31.7258 31.7003 33.5114 29.028C35.297 26.3557 36.25 23.2139 36.25 20C36.2455 15.6916 34.5319 11.561 31.4855 8.51454C28.439 5.46806 24.3084 3.75455 20 3.75ZM23.3844 25.3656C23.5005 25.4818 23.5926 25.6196 23.6555 25.7714C23.7184 25.9231 23.7507 26.0858 23.7507 26.25C23.7507 26.4142 23.7184 26.5769 23.6555 26.7286C23.5926 26.8804 23.5005 27.0182 23.3844 27.1344C23.2682 27.2505 23.1304 27.3426 22.9786 27.4055C22.8269 27.4683 22.6643 27.5007 22.5 27.5007C22.3358 27.5007 22.1731 27.4683 22.0214 27.4055C21.8696 27.3426 21.7318 27.2505 21.6156 27.1344L15.3656 20.8844C15.2494 20.7683 15.1572 20.6304 15.0943 20.4787C15.0314 20.3269 14.999 20.1643 14.999 20C14.999 19.8357 15.0314 19.6731 15.0943 19.5213C15.1572 19.3696 15.2494 19.2317 15.3656 19.1156L21.6156 12.8656C21.7318 12.7495 21.8696 12.6574 22.0214 12.5945C22.1731 12.5317 22.3358 12.4993 22.5 12.4993C22.6643 12.4993 22.8269 12.5317 22.9786 12.5945C23.1304 12.6574 23.2682 12.7495 23.3844 12.8656C23.5005 12.9818 23.5926 13.1196 23.6555 13.2714C23.7184 13.4231 23.7507 13.5858 23.7507 13.75C23.7507 13.9142 23.7184 14.0769 23.6555 14.2286C23.5926 14.3804 23.5005 14.5182 23.3844 14.6344L18.0172 20L23.3844 25.3656Z\" fill=\"#B5C0CD\"><\/path><\/svg><\/button><button class=\"swiper__arrow swiper__arrow--next carousel-swiper-button-next swiper__arrow swiper__arrow--next carousel-swiper-button-next-block_69ef30110f163\" tabindex=\"0\" aria-label=\"Next slide\"><svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"40\" height=\"40\" viewbox=\"0 0 40 40\" fill=\"none\"><path d=\"M20 3.75C16.7861 3.75 13.6443 4.70305 10.972 6.48862C8.29969 8.27419 6.21689 10.8121 4.98696 13.7814C3.75704 16.7507 3.43524 20.018 4.06225 23.1702C4.68926 26.3224 6.23692 29.2179 8.50952 31.4905C10.7821 33.7631 13.6776 35.3107 16.8298 35.9378C19.982 36.5648 23.2493 36.243 26.2186 35.013C29.1879 33.7831 31.7258 31.7003 33.5114 29.028C35.297 26.3557 36.25 23.2139 36.25 20C36.2455 15.6916 34.5319 11.561 31.4855 8.51454C28.439 5.46806 24.3084 3.75455 20 3.75ZM23.3844 25.3656C23.5005 25.4818 23.5926 25.6196 23.6555 25.7714C23.7184 25.9231 23.7507 26.0858 23.7507 26.25C23.7507 26.4142 23.7184 26.5769 23.6555 26.7286C23.5926 26.8804 23.5005 27.0182 23.3844 27.1344C23.2682 27.2505 23.1304 27.3426 22.9786 27.4055C22.8269 27.4683 22.6643 27.5007 22.5 27.5007C22.3358 27.5007 22.1731 27.4683 22.0214 27.4055C21.8696 27.3426 21.7318 27.2505 21.6156 27.1344L15.3656 20.8844C15.2494 20.7683 15.1572 20.6304 15.0943 20.4787C15.0314 20.3269 14.999 20.1643 14.999 20C14.999 19.8357 15.0314 19.6731 15.0943 19.5213C15.1572 19.3696 15.2494 19.2317 15.3656 19.1156L21.6156 12.8656C21.7318 12.7495 21.8696 12.6574 22.0214 12.5945C22.1731 12.5317 22.3358 12.4993 22.5 12.4993C22.6643 12.4993 22.8269 12.5317 22.9786 12.5945C23.1304 12.6574 23.2682 12.7495 23.3844 12.8656C23.5005 12.9818 23.5926 13.1196 23.6555 13.2714C23.7184 13.4231 23.7507 13.5858 23.7507 13.75C23.7507 13.9142 23.7184 14.0769 23.6555 14.2286C23.5926 14.3804 23.5005 14.5182 23.3844 14.6344L18.0172 20L23.3844 25.3656Z\" fill=\"#B5C0CD\"><\/path><\/svg><\/button><\/div>\n<\/div>\n<\/div>\n<p><script defer>\n    document.addEventListener('DOMContentLoaded', function() {\n        const imagesCarouselSwiper = new Swiper('.carousel-swiper-block_69ef30110f163', {\n            slidesPerView: 1,\n            spaceBetween: 20,\n            loop: true,\n            pagination: {\n                el: '.swiper-article-carousel__pagination-container-block_69ef30110f163',\n                clickable: true,\n            },\n            navigation: {\n                nextEl: '.carousel-swiper-button-next-block_69ef30110f163',\n                prevEl: '.carousel-swiper-button-prev-block_69ef30110f163',\n            },\n        })\n    })\n<\/script><\/p>\n<h2 class=\"wp-block-heading\" id=\"manifestations-cliniques\">Manifestations cliniques<\/h2>\n<p>Il se peut qu\u2019aucun sympt\u00f4me n\u2019apparaisse pendant une longue p\u00e9riode. Au fur et \u00e0 mesure que la tumeur se d\u00e9veloppe, des plaintes peuvent appara\u00eetre :   <\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u043f\u0430\u043b\u044c\u043f\u0438\u0440\u0443\u0435\u043c\u0430\u044f \u043e\u043f\u0443\u0445\u043e\u043b\u044c<\/strong> \u2014 \u043c\u0435\u0434\u043b\u0435\u043d\u043d\u043e \u0440\u0430\u0441\u0442\u0443\u0449\u0430\u044f, \u0431\u0435\u0437\u0431\u043e\u043b\u0435\u0437\u043d\u0435\u043d\u043d\u0430\u044f, \u043f\u0443\u043b\u044c\u0441\u0438\u0440\u0443\u044e\u0449\u0430\u044f \u043c\u0430\u0441\u0441\u0430 \u043d\u0430 \u0431\u043e\u043a\u043e\u0432\u043e\u0439 \u043f\u043e\u0432\u0435\u0440\u0445\u043d\u043e\u0441\u0442\u0438 \u0448\u0435\u0438 (\u0432 \u043e\u0431\u043b\u0430\u0441\u0442\u0438 \u0433\u0440\u0443\u0434\u0438\u043d\u043e-\u043a\u043b\u044e\u0447\u0438\u0447\u043d\u043e-\u0441\u043e\u0441\u0446\u0435\u0432\u0438\u0434\u043d\u043e\u0439 \u043c\u044b\u0448\u0446\u044b); \u200b<\/li>\n<li><strong>\u043d\u0435\u0432\u0440\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u044b <\/strong>\u2014 \u043e\u0441\u0438\u043f\u043b\u043e\u0441\u0442\u044c \u0433\u043e\u043b\u043e\u0441\u0430, \u0434\u0438\u0441\u0444\u0430\u0433\u0438\u044f, \u043e\u043d\u0435\u043c\u0435\u043d\u0438\u0435 \u044f\u0437\u044b\u043a\u0430, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u044b\u0435 \u043a\u043e\u043c\u043f\u0440\u0435\u0441\u0441\u0438\u0435\u0439 \u0447\u0435\u0440\u0435\u043f\u043d\u044b\u0445 \u043d\u0435\u0440\u0432\u043e\u0432 (IX\u2013XII); \u200b<\/li>\n<li><strong>\u0436<\/strong><strong>\u0430\u043b\u043e\u0431\u044b, \u0441\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0435 \u0441 \u0432\u044b\u0440\u0430\u0431\u043e\u0442\u043a\u043e\u0439 \u043a\u0430\u0442\u0435\u0445\u043e\u043b\u0430\u043c\u0438\u043d\u043e\u0432<\/strong> \u2014 \u0441\u0435\u0440\u0434\u0446\u0435\u0431\u0438\u0435\u043d\u0438\u0435, \u043f\u0440\u0438\u0441\u0442\u0443\u043f\u044b \u0430\u0440\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0439 \u0433\u0438\u043f\u0435\u0440\u0442\u0435\u043d\u0437\u0438\u0438, \u043f\u043e\u0442\u043b\u0438\u0432\u043e\u0441\u0442\u044c, \u0433\u043e\u043b\u043e\u0432\u043d\u0430\u044f \u0431\u043e\u043b\u044c, \u0442\u0440\u0435\u043c\u043e\u0440;<\/li>\n<li><strong>\u0440\u0435\u0434\u043a\u0438\u0435 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u044f<\/strong> \u2014 <strong>\u00a0<\/strong>\u0433\u043e\u043b\u043e\u0432\u043e\u043a\u0440\u0443\u0436\u0435\u043d\u0438\u0435, \u043e\u0431\u043c\u043e\u0440\u043e\u043a\u0438 \u043f\u0440\u0438 \u043a\u043e\u043c\u043f\u0440\u0435\u0441\u0441\u0438\u0438 \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u043e\u0433\u043e \u0441\u0438\u043d\u0443\u0441\u0430.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\" id=\"diagnostic-du-paragangliome\">Diagnostic du <span class=\"glossary-term\" data-title=\"Tumeur glomique\" data-tooltip=\"La tumeur glomique, ou paragangliome, est une tumeur rare, g\u00e9n\u00e9ralement b\u00e9nigne, qui se d\u00e9veloppe \u00e0 partir des cellules des paraganglions (ch\u00e9mor\u00e9cepteurs). Ces cellules r\u00e9agissent normalement aux variations de la composition chimique du sang et sont situ\u00e9es le long des gros vaisseaux sanguins et des nerfs.\" data-link=\"https:\/\/wiki.dev.voka.io\/fr\/glossaire\/tumeur-glomique\/\">paragangliome<\/span><\/h2>\n<ul class=\"wp-block-list\">\n<li><strong>\u0424\u0438\u0437\u0438\u043a\u0430\u043b\u044c\u043d\u043e\u0435 \u043e\u0431\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435: <\/strong>\u043f\u043b\u043e\u0442\u043d\u0430\u044f, \u043f\u0443\u043b\u044c\u0441\u0438\u0440\u0443\u044e\u0449\u0430\u044f \u043e\u043f\u0443\u0445\u043e\u043b\u044c \u043d\u0430 \u0448\u0435\u0435, \u0441\u043c\u0435\u0449\u0430\u044e\u0449\u0430\u044f\u0441\u044f \u043f\u043e \u0433\u043e\u0440\u0438\u0437\u043e\u043d\u0442\u0430\u043b\u0438, \u043d\u043e \u043d\u0435 \u043f\u043e \u0432\u0435\u0440\u0442\u0438\u043a\u0430\u043b\u0438. \u200b<\/li>\n<li><strong>\u0423\u0417\u0418 \u0441 \u0434\u043e\u043f\u043f\u043b\u0435\u0440\u043e\u0433\u0440\u0430\u0444\u0438\u0435<\/strong>\u0439: \u0433\u0438\u043f\u0435\u0440\u0432\u0430\u0441\u043a\u0443\u043b\u044f\u0440\u043d\u0430\u044f \u043e\u043f\u0443\u0445\u043e\u043b\u044c \u0432 \u043e\u0431\u043b\u0430\u0441\u0442\u0438 \u0431\u0438\u0444\u0443\u0440\u043a\u0430\u0446\u0438\u0438 \u0441\u043e\u043d\u043d\u043e\u0439 \u0430\u0440\u0442\u0435\u0440\u0438\u0438. \u200b<\/li>\n<li><strong>\u041c\u0420\u0422 \u0441 \u043a\u043e\u043d\u0442\u0440\u0430\u0441\u0442\u043e\u043c<\/strong>: \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u043d\u044b\u0439 \u00ab\u0441\u043e\u043b\u0435\u043d\u043e-\u043f\u0435\u0440\u0435\u0447\u043d\u044b\u0439\u00bb \u0432\u0438\u0434 \u043d\u0430 \u04221-\u0432\u0437\u0432\u0435\u0448\u0435\u043d\u043d\u044b\u0445 \u0438\u0437\u043e\u0431\u0440\u0430\u0436\u0435\u043d\u0438\u044f\u0445.<\/li>\n<li><strong>\u041a\u0422 \u0441 \u043a\u043e\u043d\u0442\u0440\u0430\u0441\u0442\u043e\u043c<\/strong>: \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0441\u0442\u0435\u043f\u0435\u043d\u0438 \u0438\u043d\u0432\u0430\u0437\u0438\u0438 \u0432 \u0441\u043e\u0441\u0443\u0434\u044b, \u043e\u0446\u0435\u043d\u043a\u0430 Shamblin-\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u0438. \u200b\u041f\u043e\u0441\u0442\u0440\u043e\u0435\u043d\u0438\u0435 3D-\u043c\u043e\u0434\u0435\u043b\u0438 \u0434\u043b\u044f \u043f\u043b\u0430\u043d\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u043e\u043f\u0435\u0440\u0430\u0446\u0438\u0438.<\/li>\n<li><strong>\u0410\u043d\u0433\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/strong>: \u0432\u044b\u044f\u0432\u043b\u0435\u043d\u0438\u0435 \u00ab\u0437\u043d\u0430\u043a\u0430 \u043b\u0438\u0440\u044b\u00bb \u2014 \u0440\u0430\u0441\u0445\u043e\u0436\u0434\u0435\u043d\u0438\u044f \u0432\u043d\u0443\u0442\u0440\u0435\u043d\u043d\u0435\u0439 \u0438 \u043d\u0430\u0440\u0443\u0436\u043d\u043e\u0439 \u0441\u043e\u043d\u043d\u044b\u0445 \u0430\u0440\u0442\u0435\u0440\u0438\u0439. \u041f\u043e\u0437\u0432\u043e\u043b\u044f\u0435\u0442 \u043e\u0446\u0435\u043d\u0438\u0442\u044c \u043d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u043e\u0441\u0442\u044c\/\u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e\u0441\u0442\u044c \u044d\u043c\u0431\u043e\u043b\u0438\u0437\u0430\u0446\u0438\u0438 \u0434\u0430\u043d\u043d\u043e\u0439 \u0437\u043e\u043d\u044b \u043a\u0430\u043a \u044d\u0442\u0430\u043f\u0430 \u043f\u0435\u0440\u0435\u0434 \u043e\u043f\u0435\u0440\u0430\u0442\u0438\u0432\u043d\u044b\u043c \u0432\u043c\u0435\u0448\u0430\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u043e\u043c. \u200b<\/li>\n<li><strong>\u041f\u042d\u0422-\u041a\u0422 \u0441 <\/strong><strong><sup>68<\/sup><\/strong><strong>Ga-DOTATATE<\/strong>: \u043f\u0440\u0438 \u043f\u043e\u0434\u043e\u0437\u0440\u0435\u043d\u0438\u0438 \u043d\u0430 \u043c\u043d\u043e\u0436\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0435 \u0438\u043b\u0438 \u043c\u0435\u0442\u0430\u0441\u0442\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043e\u0447\u0430\u0433\u0438.. \u200b<\/li>\n<li><strong>\u041b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u043d\u044b\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f<\/strong>: \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0443\u0440\u043e\u0432\u043d\u044f \u043c\u0435\u0442\u0430\u043d\u0435\u0444\u0440\u0438\u043d\u043e\u0432 \u0438 \u043d\u043e\u0440\u043c\u0435\u0442\u0430\u043d\u0435\u0444\u0440\u0438\u043d\u043e\u0432 \u0432 \u043f\u043b\u0430\u0437\u043c\u0435 \u0438 \u043c\u043e\u0447\u0435 \u043f\u0440\u0438 \u043f\u043e\u0434\u043e\u0437\u0440\u0435\u043d\u0438\u0438 \u043d\u0430 \u0441\u0435\u043a\u0440\u0435\u0442\u0438\u0440\u0443\u044e\u0449\u0443\u044e \u043e\u043f\u0443\u0445\u043e\u043b\u044c.\u200b<\/li>\n<li><strong>\u0413\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0442\u0435\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435<\/strong> \u043d\u0430 \u043c\u0443\u0442\u0430\u0446\u0438\u0438 \u0432 \u0433\u0435\u043d\u0430\u0445 <em>SDH<\/em> \u043f\u0440\u0438 \u043d\u0430\u043b\u0438\u0447\u0438\u0438 \u0441\u0435\u043c\u0435\u0439\u043d\u043e\u0433\u043e \u0430\u043d\u0430\u043c\u043d\u0435\u0437\u0430 \u0438\u043b\u0438 \u043c\u043d\u043e\u0436\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0445 \u043e\u043f\u0443\u0445\u043e\u043b\u0435\u0439.<\/li>\n<\/ul>\n<div class=\"social-banner-block\">\n<div class=\"social-banner-content\">\n<p class=\"h5-title text-black\">Retrouvez d\u2019autres contenus scientifiquement exacts sur nos m\u00e9dias sociaux<\/p>\n<p><span class=\"social-banner-text text-grey\">Abonnez-vous et ne manquez pas les derni\u00e8res ressources<\/span><\/p>\n<div class=\"social-links-wrapper\"><a class=\"social-icon-link\" href=\"https:\/\/www.facebook.com\/VOKA3DAnatomyAndPathology\/\" target=\"_blank\" rel=\"nofollow noopener\"><img decoding=\"async\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/common\/Social%20Icons\/facebook.svg\" alt=\"social link\"><\/a><a class=\"social-icon-link\" href=\"https:\/\/www.instagram.com\/voka.io\/\" target=\"_blank\" rel=\"nofollow noopener\"><img decoding=\"async\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/common\/Social%20Icons\/insta.svg\" alt=\"social link\"><\/a><a class=\"social-icon-link\" href=\"https:\/\/www.linkedin.com\/company\/voka-io\/posts\/?feedView=all\" target=\"_blank\" rel=\"nofollow noopener\"><img decoding=\"async\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/common\/Social%20Icons\/linkedin.svg\" alt=\"social link\"><\/a><a class=\"social-icon-link\" href=\"https:\/\/www.youtube.com\/@vokaio\" target=\"_blank\" rel=\"nofollow noopener\"><img decoding=\"async\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/common\/Social%20Icons\/youtube.svg\" alt=\"social link\"><\/a><a class=\"social-icon-link\" href=\"https:\/\/www.pinterest.com\/voka3danatomyandpathology\/\" target=\"_blank\" rel=\"nofollow noopener\"><img decoding=\"async\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/common\/Social%20Icons\/pinterest.svg\" alt=\"social link\"><\/a><a class=\"social-icon-link\" href=\"https:\/\/www.tiktok.com\/@voka.io\" target=\"_blank\" rel=\"nofollow noopener\"><img decoding=\"async\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/common\/Social%20Icons\/tiktok.svg\" alt=\"social link\"><\/a><a class=\"social-icon-link\" href=\"https:\/\/discord.gg\/7ejUpq8DRR\" target=\"_blank\" rel=\"nofollow noopener\"><img decoding=\"async\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/common\/Social%20Icons\/discord.svg\" alt=\"social link\"><\/a><\/div>\n<\/div>\n<p><img decoding=\"async\" class=\"social-banner-image\" loading=\"lazy\" src=\"https:\/\/storage.googleapis.com\/dev_wiki_voka_io_303011\/common\/social-media-banner-mobile-image.webp\" alt=\"Banner background\"><\/div>\n<h2 class=\"wp-block-heading\" id=\"traitement\">Traitement<\/h2>\n<p>Le traitement du ch\u00e9modectome carotidien d\u00e9pend de la taille de la tumeur, des sympt\u00f4mes cliniques, du risque de complications, de l\u2019activit\u00e9 fonctionnelle, du profil g\u00e9n\u00e9tique et du grade de Shamblin. Les principales modalit\u00e9s de traitement sont l\u2019excision chirurgicale, l\u2019<span class=\"glossary-term\" data-title=\"Embolisation\" data-tooltip=\"L\u2019embolisation est une proc\u00e9dure endovasculaire mini-invasive consistant en l\u2019occlusion cibl\u00e9e d\u2019un vaisseau sanguin par l\u2019introduction de mat\u00e9riaux sp\u00e9cifiques, appel\u00e9s emboles, dans sa lumi\u00e8re.\" data-link=\"https:\/\/wiki.dev.voka.io\/fr\/glossaire\/embolisation\/\">embolisation<\/span> pr\u00e9op\u00e9ratoire et, dans certains cas, la radioth\u00e9rapie ou la chimioth\u00e9rapie. <\/p>\n<ol class=\"wp-block-list\">\n<li><strong>Embolisation pr\u00e9op\u00e9ratoire<\/strong><\/li>\n<\/ol>\n<p>\u041f\u0440\u0435\u0434\u043e\u043f\u0435\u0440\u0430\u0446\u0438\u043e\u043d\u043d\u0430\u044f \u044d\u043c\u0431\u043e\u043b\u0438\u0437\u0430\u0446\u0438\u044f \u043f\u0440\u043e\u0432\u043e\u0434\u0438\u0442\u0441\u044f \u0441 \u0446\u0435\u043b\u044c\u044e \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u044f \u0432\u0430\u0441\u043a\u0443\u043b\u044f\u0440\u0438\u0437\u0430\u0446\u0438\u0438 \u043e\u043f\u0443\u0445\u043e\u043b\u0438, \u0443\u043c\u0435\u043d\u044c\u0448\u0435\u043d\u0438\u044f \u043e\u0431\u044a\u0435\u043c\u0430 \u0438\u043d\u0442\u0440\u0430\u043e\u043f\u0435\u0440\u0430\u0446\u0438\u043e\u043d\u043d\u043e\u0439 \u043a\u0440\u043e\u0432\u043e\u043f\u043e\u0442\u0435\u0440\u0438 \u0438 \u043e\u0431\u043b\u0435\u0433\u0447\u0435\u043d\u0438\u044f \u0432\u044b\u0434\u0435\u043b\u0435\u043d\u0438\u044f \u043e\u043f\u0443\u0445\u043e\u043b\u0438 \u043f\u0440\u0438 \u0445\u0438\u0440\u0443\u0440\u0433\u0438\u0438.<\/p>\n<p><strong>Indications<\/strong> :<\/p>\n<ul class=\"wp-block-list\">\n<li>\u043e\u043f\u0443\u0445\u043e\u043b\u0438 Shamblin II\u2013III \u043a\u043b\u0430\u0441\u0441\u0430;<\/li>\n<li>\u0434\u0438\u0430\u043c\u0435\u0442\u0440 \u043e\u043f\u0443\u0445\u043e\u043b\u0438 > 3 \u0441\u043c;<\/li>\n<li>\u043d\u0430\u043b\u0438\u0447\u0438\u0435 \u0437\u043d\u0430\u0447\u0438\u043c\u043e\u0433\u043e \u0430\u0440\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043a\u0440\u043e\u0432\u043e\u0442\u043e\u043a\u0430 (\u043f\u043e \u0434\u0430\u043d\u043d\u044b\u043c \u041a\u0422\/\u0430\u043d\u0433\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u0438);<\/li>\n<li>\u043f\u043b\u0430\u043d\u0438\u0440\u0443\u0435\u043c\u0430\u044f \u0440\u0435\u0437\u0435\u043a\u0446\u0438\u044f \u0441 \u0440\u0435\u043a\u043e\u043d\u0441\u0442\u0440\u0443\u043a\u0446\u0438\u0435\u0439 \u0441\u043e\u0441\u0443\u0434\u043e\u0432.<\/li>\n<\/ul>\n<p><strong>Contre-indications :<\/strong><\/p>\n<ul class=\"wp-block-list\">\n<li>\u043e\u043f\u0443\u0445\u043e\u043b\u0438 Shamblin I;<\/li>\n<li>\u043e\u0442\u0441\u0443\u0442\u0441\u0442\u0432\u0438\u0435 \u0430\u0440\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043a\u043e\u043c\u043f\u043e\u043d\u0435\u043d\u0442\u0430 (\u043d\u0438\u0437\u043a\u0430\u044f \u0432\u0430\u0441\u043a\u0443\u043b\u044f\u0440\u0438\u0437\u0430\u0446\u0438\u044f);<\/li>\n<li>\u0430\u043d\u0430\u0441\u0442\u043e\u043c\u043e\u0437\u044b \u0441 \u0446\u0435\u0440\u0435\u0431\u0440\u0430\u043b\u044c\u043d\u043e\u0439 \u0446\u0438\u0440\u043a\u0443\u043b\u044f\u0446\u0438\u0435\u0439 \u2014 \u0440\u0438\u0441\u043a \u044d\u043c\u0431\u043e\u043b\u0438\u0437\u0430\u0446\u0438\u0438 \u0433\u043e\u043b\u043e\u0432\u043d\u043e\u0433\u043e \u043c\u043e\u0437\u0433\u0430.<\/li>\n<\/ul>\n<p>\u0412\u044b\u043f\u043e\u043b\u043d\u044f\u0435\u0442\u0441\u044f \u0441\u0435\u043b\u0435\u043a\u0442\u0438\u0432\u043d\u0430\u044f \u0430\u043d\u0433\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f \u043d\u0430\u0440\u0443\u0436\u043d\u043e\u0439 \u0441\u043e\u043d\u043d\u043e\u0439 \u0430\u0440\u0442\u0435\u0440\u0438\u0438. \u0427\u0435\u0440\u0435\u0437 \u043c\u0438\u043a\u0440\u043e\u043a\u0430\u0442\u0435\u0442\u0435\u0440 \u043e\u0441\u0443\u0449\u0435\u0441\u0442\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0432\u0432\u0435\u0434\u0435\u043d\u0438\u0435 \u044d\u043c\u0431\u043e\u043b\u0438\u0437\u0438\u0440\u0443\u044e\u0449\u0438\u0445 \u0430\u0433\u0435\u043d\u0442\u043e\u0432: \u043f\u043e\u043b\u0438\u0432\u0438\u043d\u0438\u043b\u0430\u043b\u043a\u043e\u0433\u043e\u043b\u044c\u043d\u044b\u0445 \u0447\u0430\u0441\u0442\u0438\u0446 (PVA), \u043c\u0438\u043a\u0440\u043e\u0441\u0444\u0435\u0440, \u0440\u0435\u0436\u0435 \u2014 \u043a\u043b\u0435\u044f \u0438\u043b\u0438 \u0441\u043f\u0438\u0440\u0430\u043b\u0435\u0439. \u041a\u043e\u043d\u0442\u0440\u043e\u043b\u044c\u043d\u0430\u044f \u0430\u043d\u0433\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f \u043f\u043e\u0434\u0442\u0432\u0435\u0440\u0436\u0434\u0430\u0435\u0442 \u0440\u0435\u0434\u0443\u043a\u0446\u0438\u044e \u043a\u0440\u043e\u0432\u043e\u0442\u043e\u043a\u0430. \u041e\u043f\u0435\u0440\u0430\u0446\u0438\u044f \u043f\u0440\u043e\u0432\u043e\u0434\u0438\u0442\u0441\u044f \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 24\u201348 \u0447\u0430\u0441\u043e\u0432 \u043f\u043e\u0441\u043b\u0435 \u044d\u043c\u0431\u043e\u043b\u0438\u0437\u0430\u0446\u0438\u0438, \u043f\u043e\u043a\u0430 \u0441\u043e\u0445\u0440\u0430\u043d\u044f\u0435\u0442\u0441\u044f \u044d\u0444\u0444\u0435\u043a\u0442.<\/p>\n<ol start=\"2\" class=\"wp-block-list\">\n<li><strong>Traitement chirurgical  <\/strong><\/li>\n<\/ol>\n<p><strong>Indications<\/strong> :<\/p>\n<ul class=\"wp-block-list\">\n<li>\u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043d\u044b\u0435 \u043e\u043f\u0443\u0445\u043e\u043b\u0438 (\u0431\u043e\u043b\u044c, \u0434\u0438\u0441\u0444\u0430\u0433\u0438\u044f, \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435 \u0440\u0435\u0447\u0438);<\/li>\n<li>\u0431\u044b\u0441\u0442\u0440\u044b\u0439 \u0440\u043e\u0441\u0442 \u043e\u043f\u0443\u0445\u043e\u043b\u0438;<\/li>\n<li>\u043e\u043f\u0443\u0445\u043e\u043b\u0438 > 2,5\u20133 \u0441\u043c (\u0434\u0430\u0436\u0435 \u0431\u0435\u0441\u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043d\u044b\u0435);<\/li>\n<li>\u043f\u043e\u0434\u0442\u0432\u0435\u0440\u0436\u0434\u0435\u043d\u043d\u0430\u044f \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u043f\u043e \u041f\u042d\u0422 \u0438\u043b\u0438 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0438;<\/li>\n<li>\u043f\u043e\u0434\u0442\u0432\u0435\u0440\u0436\u0434\u0435\u043d\u043d\u0430\u044f \u043c\u0443\u0442\u0430\u0446\u0438\u044f SDHB (\u0440\u0438\u0441\u043a \u0437\u043b\u043e\u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0441\u0442\u0438);<\/li>\n<li>\u0432\u043e\u0437\u0440\u0430\u0441\u0442 < 60 \u043b\u0435\u0442.<\/li>\n<\/ul>\n<p><strong>Types de traitement chirurgical<\/strong>:<\/p>\n<ul class=\"wp-block-list\">\n<li><strong>\u042d\u043a\u0441\u0442\u0440\u0430\u043a\u0430\u043f\u0441\u0443\u043b\u044f\u0440\u043d\u0430\u044f \u0440\u0435\u0437\u0435\u043a\u0446\u0438\u044f \u043e\u043f\u0443\u0445\u043e\u043b\u0438<\/strong>. \u0421\u0442\u0430\u043d\u0434\u0430\u0440\u0442 \u0434\u043b\u044f Shamblin I\u2013II, \u0441\u043e\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u0435 \u0441\u043e\u0441\u0443\u0434\u043e\u0432, \u043c\u0438\u043d\u0438\u043c\u0430\u043b\u044c\u043d\u044b\u0439 \u0440\u0438\u0441\u043a.<\/li>\n<li><strong>\u0420\u0435\u0437\u0435\u043a\u0446\u0438\u044f \u0441\u043e\u043d\u043d\u043e\u0439 \u0430\u0440\u0442\u0435\u0440\u0438\u0438 \u0441 \u0440\u0435\u043a\u043e\u043d\u0441\u0442\u0440\u0443\u043a\u0446\u0438\u0435\u0439<\/strong>. \u0427\u0430\u0449\u0435 \u043f\u0440\u0438 Shamblin III. \u041f\u043e\u0441\u043b\u0435 \u0440\u0435\u0437\u0435\u043a\u0446\u0438\u0438 \u0443\u0447\u0430\u0441\u0442\u043a\u0430 \u0441\u043e\u043d\u043d\u043e\u0439 \u0430\u0440\u0442\u0435\u0440\u0438\u0438 \u0432\u044b\u043f\u043e\u043b\u043d\u044f\u0435\u0442\u0441\u044f \u043f\u0440\u043e\u0442\u0435\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 (Dacron, PTFE).\u00a0<\/li>\n<li><strong>Neuromonitoring et microchirurgie<\/strong>. Utilis\u00e9 \u00e0 proximit\u00e9 des nerfs cr\u00e2niens (IX-XII).<\/li>\n<\/ul>\n<p><strong>Complications possibles<\/strong> :<\/p>\n<ul class=\"wp-block-list\">\n<li>\u043a\u0440\u043e\u0432\u043e\u0442\u0435\u0447\u0435\u043d\u0438\u0435 (\u043e\u0441\u043e\u0431\u0435\u043d\u043d\u043e \u043f\u0440\u0438 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0439 \u044d\u043c\u0431\u043e\u043b\u0438\u0437\u0430\u0446\u0438\u0438);<\/li>\n<li>\u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u0435 \u0447\u0435\u0440\u0435\u043f\u043d\u044b\u0445 \u043d\u0435\u0440\u0432\u043e\u0432 (IX\u2013XII) \u2014 \u0434\u043e 30\u00a0% \u043f\u0440\u0438 \u043a\u0440\u0443\u043f\u043d\u044b\u0445 \u043e\u043f\u0443\u0445\u043e\u043b\u044f\u0445;<\/li>\n<li>\u0438\u043d\u0441\u0443\u043b\u044c\u0442 (\u043f\u0440\u0438 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0438 \u043a\u043e\u043b\u043b\u0430\u0442\u0435\u0440\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043a\u0440\u043e\u0432\u043e\u0442\u043e\u043a\u0430);<\/li>\n<li>\u0440\u0435\u0446\u0438\u0434\u0438\u0432 (\u0440\u0435\u0434\u043a\u043e, \u043f\u0440\u0438 \u043d\u0435\u043f\u043e\u043b\u043d\u043e\u0439 \u0440\u0435\u0437\u0435\u043a\u0446\u0438\u0438).<\/li>\n<\/ul>\n<ol start=\"3\" class=\"wp-block-list\">\n<li><strong>Chimioth\u00e9rapie  <\/strong><\/li>\n<\/ol>\n<p>Il ne s\u2019agit pas d\u2019un traitement standard du ch\u00e9modectome carotidien, car la plupart des tumeurs ont une croissance lente et sont de nature b\u00e9nigne. Toutefois, dans les rares cas d\u2019\u00e9volution maligne (progression rapide, l\u00e9sions m\u00e9tastatiques) ou dans les formes m\u00e9tastatiques inop\u00e9rables, un traitement syst\u00e9mique peut \u00eatre utilis\u00e9. <\/p>\n<ol start=\"4\" class=\"wp-block-list\">\n<li><strong><strong>\u0420\u0430\u0434\u0438\u043e\u043d\u0443\u043a\u043b\u0438\u0434\u043d\u0430\u044f \u0442\u0435\u0440\u0430\u043f\u0438\u044f \u00b9\u2077\u2077Lu-DOTATATE (PRRT)\u00a0<\/strong><\/strong><\/li>\n<\/ol>\n<p>Prescrit en pr\u00e9sence d\u2019une expression des r\u00e9cepteurs de la somatostatine par TEP avec \u2076\u2078\u2078Ga-DOTATATE.<\/p>\n<div>\n<h2 class=\"faq-title h2-article\" id=\"faq\">FAQ<\/h2>\n<div class=\"faq-section\">\n<div class=\"faq-item faq-answer-hidden\">\n<div class=\"question-block\">\n<div class=\"faq-question\">\n<p class=\" text-black h5-title\">1. Le ch\u00e9modectome carotidien est-il une tumeur maligne ?<\/p>\n<\/div>\n<div class=\"faq-answer text-main-text-color main-text-medium\">\u0412 \u0431\u043e\u043b\u044c\u0448\u0438\u043d\u0441\u0442\u0432\u0435 \u0441\u043b\u0443\u0447\u0430\u0435\u0432 \u2014 \u043d\u0435\u0442. \u041a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u0430\u044f \u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430 \u043e\u0442\u043d\u043e\u0441\u0438\u0442\u0441\u044f \u043a \u0434\u043e\u0431\u0440\u043e\u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u043c, \u043c\u0435\u0434\u043b\u0435\u043d\u043d\u043e \u0440\u0430\u0441\u0442\u0443\u0449\u0438\u043c \u043e\u043f\u0443\u0445\u043e\u043b\u044f\u043c. \u041e\u0434\u043d\u0430\u043a\u043e \u043f\u0440\u0438 \u043d\u0430\u043b\u0438\u0447\u0438\u0438 \u043c\u0443\u0442\u0430\u0446\u0438\u0439 \u0433\u0435\u043d\u0430 <em>SDHB<\/em> \u0432\u043e\u0437\u043c\u043e\u0436\u0435\u043d \u0437\u043b\u043e\u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b \u0441 \u043c\u0435\u0442\u0430\u0441\u0442\u0430\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435\u043c.<\/div>\n<\/div>\n<div class=\"expand-button-wrapper\"><button class=\"text-accent expand-button\">+<\/button><\/div>\n<\/div>\n<div class=\"faq-item faq-answer-hidden\">\n<div class=\"question-block\">\n<div class=\"faq-question\">\n<p class=\" text-black h5-title\">2. \u041c\u043e\u0436\u043d\u043e \u043b\u0438 \u043f\u0440\u043e\u0441\u0442\u043e \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0442\u044c \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u0443\u044e \u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0443, \u043d\u0435 \u0443\u0434\u0430\u043b\u044f\u044f \u0435\u0435?<\/p>\n<\/div>\n<div class=\"faq-answer text-main-text-color main-text-medium\">\u0414\u0430, \u0432 \u043d\u0435\u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0441\u043b\u0443\u0447\u0430\u044f\u0445 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0435 \u043d\u0430\u0431\u043b\u044e\u0434\u0435\u043d\u0438\u0435, \u043e\u0441\u043e\u0431\u0435\u043d\u043d\u043e \u0435\u0441\u043b\u0438 \u043e\u043f\u0443\u0445\u043e\u043b\u044c \u043d\u0435\u0431\u043e\u043b\u044c\u0448\u0430\u044f (< 2,5 \u0441\u043c), \u0431\u0435\u0441\u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043d\u0430\u044f, \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430 \u043f\u043e\u0436\u0438\u043b\u043e\u0439 \u0432\u043e\u0437\u0440\u0430\u0441\u0442 \u0438\u043b\u0438 \u0435\u0441\u0442\u044c \u043f\u0440\u043e\u0442\u0438\u0432\u043e\u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f \u043a \u043e\u043f\u0435\u0440\u0430\u0446\u0438\u0438. \u041e\u0434\u043d\u0430\u043a\u043e \u043f\u0440\u0438 \u043f\u0440\u0438\u0437\u043d\u0430\u043a\u0430\u0445 \u0440\u043e\u0441\u0442\u0430 \u0438\u043b\u0438 \u043a\u043e\u043c\u043f\u0440\u0435\u0441\u0441\u0438\u0438 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440 \u0448\u0435\u0438 \u0442\u0440\u0435\u0431\u0443\u0435\u0442\u0441\u044f \u043b\u0435\u0447\u0435\u043d\u0438\u0435.<\/div>\n<\/div>\n<div class=\"expand-button-wrapper\"><button class=\"text-accent expand-button\">+<\/button><\/div>\n<\/div>\n<div class=\"faq-item faq-answer-hidden\">\n<div class=\"question-block\">\n<div class=\"faq-question\">\n<p class=\" text-black h5-title\">3. L\u2019ablation chirurgicale d\u2019un ch\u00e9modectome carotidien est-elle dangereuse ?<\/p>\n<\/div>\n<div class=\"faq-answer text-main-text-color main-text-medium\">Les risques d\u00e9pendent de la taille et de la localisation de la tumeur. En cas de masse importante, des complications sont possibles, notamment des l\u00e9sions du nerf cr\u00e2nien, des h\u00e9morragies et des accidents isch\u00e9miques. Une embolisation pr\u00e9op\u00e9ratoire est souvent r\u00e9alis\u00e9e pour r\u00e9duire les risques.  <\/div>\n<\/div>\n<div class=\"expand-button-wrapper\"><button class=\"text-accent expand-button\">+<\/button><\/div>\n<\/div>\n<div class=\"faq-item faq-answer-hidden\">\n<div class=\"question-block\">\n<div class=\"faq-question\">\n<p class=\" text-black h5-title\">4. Les autres membres de la famille doivent-ils \u00eatre examin\u00e9s si l\u2019on me diagnostique un chimiodectome ?<\/p>\n<\/div>\n<div class=\"faq-answer text-main-text-color main-text-medium\">\u0415\u0441\u043b\u0438 \u0443 \u0432\u0430\u0441 \u0432\u044b\u044f\u0432\u043b\u0435\u043d\u0430 \u043d\u0430\u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f \u043c\u0443\u0442\u0430\u0446\u0438\u044f (\u043d\u0430\u043f\u0440\u0438\u043c\u0435\u0440, <em>SDHD<\/em>, <em>SDHB<\/em>), \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0443\u0435\u0442\u0441\u044f \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u043a\u043e\u043d\u0441\u0443\u043b\u044c\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 \u0438 \u043e\u0431\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u0431\u043b\u0438\u0436\u0430\u0439\u0448\u0438\u0445 \u0440\u043e\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u0438\u043a\u043e\u0432, \u043f\u043e\u0441\u043a\u043e\u043b\u044c\u043a\u0443 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0435 \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0441\u0435\u043c\u0435\u0439\u043d\u044b\u043c.<\/div>\n<\/div>\n<div class=\"expand-button-wrapper\"><button class=\"text-accent expand-button\">+<\/button><\/div>\n<\/div>\n<div class=\"faq-item faq-answer-hidden\">\n<div class=\"question-block\">\n<div class=\"faq-question\">\n<p class=\" text-black h5-title\">5. Comment distinguer le ch\u00e9modectome carotidien des autres tumeurs du cou ?<\/p>\n<\/div>\n<div class=\"faq-answer text-main-text-color main-text-medium\">Le ch\u00e9modectome carotidien est g\u00e9n\u00e9ralement situ\u00e9 \u00e0 la bifurcation de l\u2019art\u00e8re carotide commune, il est pulsatile, se d\u00e9place horizontalement mais pas verticalement et pr\u00e9sente le \u00ab signe de la lyre \u00bb caract\u00e9ristique au <span class=\"glossary-term\" data-title=\"Tomodensitom\u00e9trie\" data-tooltip=\"La tomodensitom\u00e9trie est une technique de radiodiagnostic qui utilise des rayons X pour obtenir des images en coupe des organes et des tissus internes. C&#039;est une des m\u00e9thodes d&#039;imagerie principales de la m\u00e9decine moderne, caract\u00e9ris\u00e9e par une grande capacit\u00e9 d&#039;information.\" data-link=\"https:\/\/wiki.dev.voka.io\/fr\/glossaire\/tdm-tomodensitometrie\/\">scanner<\/span>\/\u00e0 l\u2019<span class=\"glossary-term\" data-title=\"IRM (imagerie par r\u00e9sonance magn\u00e9tique)\" data-tooltip=\"L&#039;imagerie par r\u00e9sonance magn\u00e9tique (IRM) est une technique moderne et non invasive de radiodiagnostic qui permet d&#039;obtenir des images en coupe des organes et des tissus internes. Cet examen repose sur le ph\u00e9nom\u00e8ne de r\u00e9sonance magn\u00e9tique nucl\u00e9aire. Le principal avantage de l&#039;IRM est l&#039;absence de rayonnements ionisants (radiation).\" data-link=\"https:\/\/wiki.dev.voka.io\/fr\/glossaire\/irm\/\">IRM<\/span>. Le diagnostic est clarifi\u00e9 par l\u2019imagerie et l\u2019angiographie. <\/div>\n<\/div>\n<div class=\"expand-button-wrapper\"><button class=\"text-accent expand-button\">+<\/button><\/div>\n<\/div>\n<div class=\"faq-item faq-answer-hidden\">\n<div class=\"question-block\">\n<div class=\"faq-question\">\n<p class=\" text-black h5-title\">6. Un ch\u00e9modectome peut-il provoquer une douleur ou une g\u00eane ?<\/p>\n<\/div>\n<div class=\"faq-answer text-main-text-color main-text-medium\">Dans la plupart des cas, non, surtout aux premiers stades. Cependant, \u00e0 mesure que la tumeur se d\u00e9veloppe, elle peut exercer une pression sur les nerfs et les vaisseaux sanguins, entra\u00eenant des douleurs, un enrouement de la voix, des troubles de la d\u00e9glutition ou des vertiges. <\/div>\n<\/div>\n<div class=\"expand-button-wrapper\"><button class=\"text-accent expand-button\">+<\/button><\/div>\n<\/div>\n<div class=\"faq-item faq-answer-hidden\">\n<div class=\"question-block\">\n<div class=\"faq-question\">\n<p class=\" text-black h5-title\">7. Y a-t-il un risque de r\u00e9cidive apr\u00e8s l\u2019ablation de la tumeur ?<\/p>\n<\/div>\n<div class=\"faq-answer text-main-text-color main-text-medium\">\u041f\u0440\u0438 \u043f\u043e\u043b\u043d\u043e\u043c \u0443\u0434\u0430\u043b\u0435\u043d\u0438\u0438 \u043e\u043f\u0443\u0445\u043e\u043b\u0438 \u0440\u0438\u0441\u043a \u0440\u0435\u0446\u0438\u0434\u0438\u0432\u0430 \u043d\u0438\u0437\u043a\u0438\u0439 (\u043c\u0435\u043d\u0435\u0435 5 %). \u041e\u0434\u043d\u0430\u043a\u043e \u043f\u0440\u0438 \u043d\u0435\u043f\u043e\u043b\u043d\u043e\u0439 \u0440\u0435\u0437\u0435\u043a\u0446\u0438\u0438, \u043d\u0430\u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0439 \u0444\u043e\u0440\u043c\u0435 \u0438\u043b\u0438 \u043d\u0430\u043b\u0438\u0447\u0438\u0438 <em>SDHB<\/em>-\u043c\u0443\u0442\u0430\u0446\u0438\u0438, \u0432\u043e\u0437\u043c\u043e\u0436\u0435\u043d \u0440\u0435\u0446\u0438\u0434\u0438\u0432 \u0438\u043b\u0438 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u0435 \u043d\u043e\u0432\u044b\u0445 \u043e\u0447\u0430\u0433\u043e\u0432. \u0412 \u0442\u0430\u043a\u0438\u0445 \u0441\u043b\u0443\u0447\u0430\u044f\u0445 \u0432\u0430\u0436\u043d\u043e \u0434\u043e\u043b\u0433\u043e\u0441\u0440\u043e\u0447\u043d\u043e\u0435 \u043d\u0430\u0431\u043b\u044e\u0434\u0435\u043d\u0438\u0435.<\/div>\n<\/div>\n<div class=\"expand-button-wrapper\"><button class=\"text-accent expand-button\">+<\/button><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"sources-list-block sources-list-hidden\" id=\"liste-des-sources\">\n<div class=\"sources-list-content\">\n<div class=\"sources-list-title\">\n<p class=\"small-text-bold text-black sources-list-title-text\">Liste des sources<\/p>\n<div class=\"sources-expand-button-wrapper-mobile\">\n<div class=\"sources-expand-button\"><svg width=\"32\" height=\"32\" viewbox=\"0 0 32 32\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M8 12L16 20L24 12\" stroke=\"#8C9AAB\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><\/path><\/svg><\/div>\n<\/div>\n<\/div>\n<div class=\"sources-list-items\">\n<div class=\"source-item\">\n<p class=\"main-text-semibold text-black\">1.<\/p>\n<div class=\"source-item-content\">\n<p class=\"main-text-semibold text-black\"><cite>VOKA 3D Anatomy & Pathology \u2013 Complete Anatomy and Pathology 3D Atlas [Internet]. VOKA 3D Anatomy & Pathology. <\/cite><\/p>\n<p><span class=\"small-text-medium text-grey\">Available from: https:\/\/catalog.voka.io\/<\/span><\/div>\n<\/div>\n<div class=\"source-item\">\n<p class=\"main-text-semibold text-black\">2.<\/p>\n<div class=\"source-item-content\">\n<p class=\"main-text-semibold text-black\"><cite>Luna-Ortiz K, Reynoso-Nover\u00f3n N, Herrera-Ponzanelli C, Favila-Lira S, Luna-Peteuil Z, Herrera-Gomez A, et al. Sex differences according to ethnic presentation in carotid body tumors: a systematic literature review. Int J Otorhinolaryngol Head Neck Surg. 2022 Jun;8(6):527-531. doi: 10.18203\/issn.2454-5929.ijohns20221393. <\/cite><\/p>\n<\/div>\n<\/div>\n<div class=\"source-item\">\n<p class=\"main-text-semibold text-black\">3.<\/p>\n<div class=\"source-item-content\">\n<p class=\"main-text-semibold text-black\"><cite>Butt N, Baek WK, Lachkar S, Iwanaga J, Mian A, Blaak C, et al. The carotid body and associated tumors: updated review with clinical\/surgical significance. Br J Neurosurg. 2019 Oct;33(5):500-503. doi: 10.1080\/02688697.2019.1617404.<\/cite><\/p>\n<\/div>\n<\/div>\n<div class=\"source-item\">\n<p class=\"main-text-semibold text-black\">4.<\/p>\n<div class=\"source-item-content\">\n<p class=\"main-text-semibold text-black\"><cite>Darouassi Y, Alaoui M, Mliha Touati M, Al Maghraoui O, En-Nouali A, Bouaity B, Ammar H. Carotid Body Tumors: A Case Series and Review of the Literature. Ann Vasc Surg. 2017 Aug;43:265-271. doi: 10.1016\/j.avsg.2017.03.167.<\/cite><\/p>\n<\/div>\n<\/div>\n<div class=\"source-item\">\n<p class=\"main-text-semibold text-black\">5.<\/p>\n<div class=\"source-item-content\">\n<p class=\"main-text-semibold text-black\"><cite>Gonzalez-Urquijo M, Castro-Varela A, Barrios-Ruiz A, Hinojosa-Gonzalez DE, Salas AKG, Morales EA, et al. Current trends in carotid body tumors: comprehensive review. Head Neck. 2022 Oct;44(10):2316-2332. doi: 10.1002\/hed.27147.<\/cite><\/p>\n<\/div>\n<\/div>\n<div class=\"source-item\">\n<p class=\"main-text-semibold text-black\">6.<\/p>\n<div class=\"source-item-content\">\n<p class=\"main-text-semibold text-black\"><cite>Ozawa H. Current management of carotid body tumors. Auris Nasus Larynx. 2024 Jun;51(3):501-506. doi: 10.1016\/j.anl.2024.01.007.<\/cite><\/p>\n<\/div>\n<\/div>\n<div class=\"source-item\">\n<p class=\"main-text-semibold text-black\">7.<\/p>\n<div class=\"source-item-content\">\n<p class=\"main-text-semibold text-black\"><cite>Piazza C, Lancini D, Tomasoni M, Zafereo M, Poorten VV, Hanna E, et al. Malignant carotid body tumors: what we know, what we do, and what we need to achieve. A systematic review of the literature. Head Neck. 2024 Mar;46(3):672-687. doi: 10.1002\/hed.27624.<\/cite><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"sources-expand-button-wrapper\">\n<div class=\"sources-expand-button\"><svg width=\"32\" height=\"32\" viewbox=\"0 0 32 32\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M8 12L16 20L24 12\" stroke=\"#8C9AAB\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><\/path><\/svg><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u041f\u0430\u0440\u0430\u0433\u0430\u043d\u0433\u043b\u0438\u043e\u043c\u0430 \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u043e\u0433\u043e \u0442\u0435\u043b\u044c\u0446\u0430 (\u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430) \u2014 \u0440\u0435\u0434\u043a\u0430\u044f, \u043f\u0440\u0435\u0438\u043c\u0443\u0449\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e \u0434\u043e\u0431\u0440\u043e\u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f \u043e\u043f\u0443\u0445\u043e\u043b\u044c, \u0432\u043e\u0437\u043d\u0438\u043a\u0430\u044e\u0449\u0430\u044f \u0438\u0437 \u0445\u0435\u043c\u043e\u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u043d\u044b\u0445 \u043a\u043b\u0435\u0442\u043e\u043a \u043a\u0430\u0440\u043e\u0442\u0438\u0434\u043d\u043e\u0433\u043e \u0442\u0435\u043b\u0430, \u0440\u0430\u0441\u043f\u043e\u043b\u043e\u0436\u0435\u043d\u043d\u043e\u0433\u043e \u0432 \u043c\u0435\u0441\u0442\u0435 \u0431\u0438\u0444\u0443\u0440\u043a\u0430\u0446\u0438\u0438 \u043e\u0431\u0449\u0435\u0439 \u0441\u043e\u043d\u043d\u043e\u0439 \u0430\u0440\u0442\u0435\u0440\u0438\u0438. \u00c9pid\u00e9miologie \u00c9tiologie \u0413\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043c\u0443\u0442\u0430\u0446\u0438\u0438 \u2014 \u0432\u0435\u0434\u0443\u0449\u0443\u044e \u0440\u043e\u043b\u044c \u0438\u0433\u0440\u0430\u044e\u0442 \u043c\u0443\u0442\u0430\u0446\u0438\u0438 \u0432 \u0433\u0435\u043d\u0430\u0445, \u043a\u043e\u0434\u0438\u0440\u0443\u044e\u0449\u0438\u0445 \u0441\u0443\u0431\u044a\u0435\u0434\u0438\u043d\u0438\u0446\u044b \u0441\u0443\u043a\u0446\u0438\u043d\u0430\u0442\u0434\u0435\u0433\u0438\u0434\u0440\u043e\u0433\u0435\u043d\u0430\u0437\u043d\u043e\u0433\u043e \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u0430 (SDH), \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u0443\u0447\u0430\u0441\u0442\u0432\u0443\u0435\u0442 \u0432 \u0434\u044b\u0445\u0430\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0446\u0435\u043f\u0438 \u043c\u0438\u0442\u043e\u0445\u043e\u043d\u0434\u0440\u0438\u0439 \u0438 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u043c \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c\u0435. \u041e\u0441\u043d\u043e\u0432\u043d\u044b\u0435 \u0433\u0435\u043d\u044b: \u0421\u0438\u043d\u0434\u0440\u043e\u043c\u044b, \u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0435 \u0441 \u0445\u0435\u043c\u043e\u0434\u0435\u043a\u0442\u043e\u043c\u0430\u043c\u0438:\u00a0 \u0425\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0433\u0438\u043f\u043e\u043a\u0441\u0438\u044f [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"template":"","diseases_category":[234],"class_list":["post-664","diseases_post","type-diseases_post","status-publish","hentry","diseases_category-systeme-vasculaire"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.0 (Yoast SEO v26.5) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Paragangliome de la carotide (ch\u00e9modectome) du cou : sympt\u00f4mes, diagnostic, traitement<\/title>\n<meta name=\"description\" content=\"Le paragangliome (ch\u00e9modectome) est une tumeur rare, essentiellement b\u00e9nigne, des cellules chimior\u00e9ceptrices de la zone de bifurcation carotidienne. 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